幽门螺旋菌感染的家庭内群集性  

INTRAFAMILIAL CLUSTERING OF HELICOBACTER PYLORI INFECTION

作　　者：邓碧儿[1] 魏曼[1] 诸庆璋[1] 

机构地区：[1]上海第二医科大学附属仁济医院儿科,200001

出　　处：《中华儿童保健杂志》1994年第2期84-85,89,共3页

摘　　要：对61位有消化道症状,经胃电图,胃十二指肠气钡双重造影或胃镜证实为胃炎、十二指肠炎或消化性溃疡的病儿及其家庭成员,用ELISA检测血清幽门螺旋菌抗体。在40例HP(+)的患儿中,有36个家庭存在血清HP抗体(占90%);总共检测121个家庭成员,HP(+)有108人(占89.26％),而21例HP(-)的患儿中,仅11个家庭成员存在HP抗体(52.26％),总共检测54个家庭成员,13人有HP(+)(24.07％)。两组结果有显著差异,证实了HP感染的家庭内群集性,提示了HP感染存在人——人传播或家庭成员共同暴露于同一传染源的可能性。61 Patients with gastrointestinal symptoms were diagnosed for gastritis, is or peptic ulcer by E. G.C. (electro gastrography) GI and/or endoscope. The Serum antibody of H. Pylori .Was examined for them and their familial members by ELISA. Positive H. Pylori antibody was detected in 36 families of 40 cases with H. Pylori positive serum antibody (90%). Among 121 familial members who were examined for H. Pylori serum antibody there were 108 existing positive H. Pylori antibody (89. 26%). But only eleven families in 21 cases with H. Pylori serum antibody negative were H. Pylori positive (52. 26%). Among 54 familial members who were examined for H. Pylori serum antibody there were 13 existing postive H. Pylori antibody (24. 07%). there was a marked difference in the two grotips. The results showed that there was intrafamilial clustering of H. pylori infection. It suggested that there is person to person transmission or common source exposure of familial members in H. Pylori infection.

关 键 词：幽门螺旋菌 胃炎 消化性溃疡 轿清 群集性 家庭 

分 类 号：R573.01[医药卫生—消化系统]