经内镜球囊扩张结合根除幽门螺杆菌治疗溃疡病幽门梗阻  

Endoscopic Balloon Dilatation Combined with Helicobacter Pylori Eradication for Treatment of Ulcer-induced Pyloric Stenosis

作　　者：刘德良[1] 霍继荣[1] 吴小平[1] 周芝元[1] 

机构地区：[1]中南大学湘雅二医院消化内科,湖南长沙410011

出　　处：《医学临床研究》2005年第7期878-880,共3页Journal of Clinical Research

摘　　要：【目的】探讨经内镜球囊扩张结合根除幽门螺杆菌(HP)治疗溃疡病幽门梗阻的疗效和安全性。【方法】对20例溃疡病并幽门梗阻患者采用CRE气囊扩张,联合质子泵抑制剂+阿莫西林+克拉霉素三联方案根除HP。术后定期随访和检查,观察患者临床症状缓解与复发、内镜或X线检查结果。【结果】20例患者经内镜气囊扩张后症状都得到缓解,未发生穿孔、呕血或黑便等并发症。16例可能存在HP感染的患者,经14C尿素呼气试验检查证实成功根除HP。术后随访6～26个月,平均16个月。扩张后6个月、18个月症状缓解率分别为95.0%(19/20)、88.9%(8/9),症状复发率分别为5.0%(1/20)、11.1%(1/9)。【结论】经内镜球囊扩张结合根除HP是治疗溃疡病幽门梗阻安全、有效的方法。[Objective]To evaluate the efficacy and safety of endoscopic balloon dilatation combined with Helicobacter pylori eradication for treatment of ulcer-induced pyloric stenosis.[Methods]Patients with ulcer-induced pyloric stenosis, whose H. pylori were eradicated with PPI+ Amoxicillin + Clarithromycin, were treated by the CRE balloon under endoscopy, followed up survey by endoscopy and barium radiography as well as symptoms were investigated periodically.[Results]The symptoms of pylori obstruction remitted in all of the 20 patients and there were no complication of perforation, haematemesis and melena. H.pylori in 16 of 20 patients were eradicated successfully. The following up ranged from 6 to 26 months, averaging 16 months. The rate of remission of pyloric obstruction symptoms was 95.0%(19/20) at six months and 88.9%(8/9) at 18 months, and the rate of recurrence of symptoms was 5.0%(1/20) 、11.1%(1/9), respectively.[Conclusion]Endoscopic balloon dilatation combined with Helicobacter pylori eradication for treatment of ulcer-induced pyloric stenosis is an effective and safe method.

关 键 词：消化性溃疡/并发症 幽门狭窄/治疗 螺杆菌 幽门 螺杆菌感染 内窥镜检查 

分 类 号：R573.6[医药卫生—消化系统]