调脂药物作用新靶点  

New targets of lipid-regulating drugs

作　　者：宋芳[1] 谢梅林[1] 顾振伦[1] 

机构地区：[1]苏州大学医学院药理学教研室,苏州中药研究所江苏苏州215007

出　　处：《中国药理学通报》2005年第7期786-789,共4页Chinese Pharmacological Bulletin

摘　　要：高脂血症是动脉粥样硬化和冠心病发生发展的主要高危因素之一。调脂药物通过调控脂质的代谢来降低血脂,进而降低心血管疾病的发生。近几年,人们发现了几种新的药物作用靶点,通过对这些新靶点的研究,有望开发出更安全有效的调脂药物。Hyperlipidemia is a major risk factor for the generation and development of atherosclerosis and coronary heart disease. The lipid-lowering effects of drugs were mediated by the control of lipid metabolism.Recently some new targets in the process of lipid metabolism were found,they may lead to the development of new drugs.

关 键 词：调血脂药 靶点 高脂血症 

分 类 号：R394.2[医药卫生—医学遗传学] R589.205[医药卫生—基础医学]