Rh蛋白家族及Rh复合体  

Rh Protein Family and Rh Complex

作　　者：李勤[1] 王玲玲[1] 钱旻[1] 朱自严[2] 

机构地区：[1]华东师范大学生命科学学院,上海市200062 [2]上海市血液中心,上海市200051

出　　处：《医学分子生物学杂志》2005年第4期302-305,共4页Journal of Medical Molecular Biology

摘　　要：Rh血型系统的抗原具有强烈免疫原性,主要由RhD、RhCE蛋白携带。RhAG糖蛋白是一类重要的Rh相关蛋白,影响Rh蛋白在红细胞表面的表达。近年来发现红细胞膜表面的其它一些蛋白,诸如LW糖蛋白、血型糖蛋白B,可参与Rh复合体的形成。Rh复合体是近年研究热点。目前已发现Rh复合体除携带Rh抗原外,还影响红细胞的形态稳定,可能还具有离子通道功能。The antigens of Rh blood group system, which are carried by RhD and RhCE proteins, have strong antigenicity. RhAG glycoprotein is an important Rh-associated protein, which can influence the expression of Rh protrins on red blood cells. Recently, some other proteins, such as LW glycoprotein and Glycophorin B, were found to be involved in the construction of Rh complex. Rh complex carries Rh antigene, maintains the configuration of red blood cells and may serves as channel for ammonium transport.

关 键 词：复合体 h蛋白 家族 RH血型系统 离子通道功能 红细胞表面 免疫原性 相关蛋白 胞膜表面 糖蛋白B 研究热点 RH抗原 RHD E蛋白 RhC 

分 类 号：R783.1[医药卫生—口腔医学] R511.1[医药卫生—临床医学]