非甾体抗炎药相关性溃疡并出血的临床分析  

Clinical analysis of non-steroidal anti-inflammatory drugs induced peptic ulcer hemorrhage

作　　者：张琳[1] 甘少光[1] 严衍伟[1] 

机构地区：[1]广东省肇庆市第一人民医院消化内科,526021

出　　处：《现代消化及介入诊疗》2005年第2期67-69,共3页Modern Interventional Diagnosis and Treatment in Gastroenterology

摘　　要：目的探讨非甾体抗炎药相关性溃疡并出血的临床及内镜特点。方法对196例消化性溃疡并出血病人的临床资料进行回顾性分析,根据出血前1周内是否服用NSAIDs分为NSAIDs组(55例)和非NSAIDs组(141例),并进行分析比较。结果NSAIDs组与非NSAIDs组在年龄、溃疡类型、溃疡数目、临床症状及Hp感染等方面均有显著差异。结论加强对非甾体抗炎药相关性溃疡并出血的认识,并采取相应措施,以减少非甾体抗炎药对胃肠道产生的毒副作用。Objective To analyze the clinical and endoscopic characteristics of non-steroidal anti- inflammatory drugs (NSAIDs) induced gastric ulcer hemorrhage. Methods The clinical data of 196 patients with gastroduedenal ulcer hemorrhage were analyzed retrospectively. The patients were randomly divided into NSAIDs group (n = 55) and no NSAIDs group (n = 141) base on whether or not NSAIDs were taken within one week before the onset of hemorrhage. Results There was significantly difference between NSAIDs group and no NSAIDs group in age of patients, types of ulcer, number of ulcer, clinical symptom and helicobacter pylori (Hp) infection. Conclusion The clinical characteristics of NSAIDs induced gastroduedenal ulcer hemorrhage should be better understood, and the relevant measures should be taken so as to reduce the adverse effect of NSAIDs

关 键 词：非甾体抗炎药 消化性溃疡 消化道出血 NSAIDS 恶性溃疡 

分 类 号：R573.1[医药卫生—消化系统] R971.1[医药卫生—内科学]