卵巢无性细胞瘤60例临床回顾分析  

Dysgerminoma of the Ovary:A Clinical Retrospective Analysis of 60 Cases

作　　者：张蓉[1] 洪婉君[1] 李淑敏[1] 张询[1] 

机构地区：[1]中国医学科学院肿瘤医院妇科

出　　处：《中华妇产科杂志》1995年第9期550-552,共3页Chinese Journal of Obstetrics and Gynecology

摘　　要：我院自１９５９年５月至１９９２年１０月收治了纯型卵巢无性细胞瘤６０例。中位年龄２１岁。主要症状为腹部包块、腹痛、腹胀。Ⅰ期患者３２例，Ⅱ期２例，Ⅲ期５例，复发或未控２１例。除１例仅行手术外，其余均接受手术加放射治疗和（或）化疗。９例死于本病，５年存活率达８５．１７％。辅助治疗采用放射治疗或化疗，两者的５年存活率差异无显著性，但对一些年轻且要求生育或晚期患者，术后采用化疗做为辅助治疗可能是更好的选择。bjective To study the treatment methods and the prognostic factors of pure dysgerminoma of the ovary.Methods Sixty cases histologically confirmed pure ovarian dysgerminoma treated in our hospi-tal, from May 1959 to Oct. 1992 were retrospectively analysed. Factors mainly studied were:age,symptoms,clinical staging and treatment methods.Results The median age of this series was 21.The main symptoms were abdominal mass,pain and distension,Thirty two out of 60 cases were stageⅠ,2 were stage Ⅱ, 5 were stage Ⅲ and 21 with recurrences or persistence of the disease, All cases excepting one case received surgery alone were treated by surgery cotribined with external radiotherapy or chemotherapy,Nine cases died of the dis-ease. The actual 5-year survival rate was 85.17%. The survival rate for patients with postoperative adjuvant chemotherapy is 95%and that for patients with radiotherapy is 76.1%; no statistic signifi- cance was shown.Conclusions In pure ovarian dysgerminoma surgery combined with radiotherapy or chemothera-py showed high complete remission rates and excellent survival rates. For younger patients and those with gestation desires as well as patients with advanced diseases,adjuvant chemotherapy following surgery might be a better choice

关 键 词：无性细胞瘤 卵巢肿瘤 外科手术 放射疗法 

分 类 号：R737.310.5[医药卫生—肿瘤]