正常眼压性青光眼患者及正常人双眼眼压波动趋势的不对称性研究  

The tendency of the diurnal IOP variations among NTG patients and normal individuals

作　　者：贠洪敏[1] 傅培[2] 黎晓新[1] 

机构地区：[1]北京大学人民医院眼科,北京100044 [2]北京大学深圳医院眼科

出　　处：《中国实用眼科杂志》2005年第7期715-718,共4页Chinese Journal of Practical Ophthalmology

摘　　要：目的探讨正常眼压性青光眼患者及正常人双眼眼压波动趋势是否一致,以指导临床抗青光眼药物的使用。方法以Goldmann压平眼压计测量11名正常眼压性青光眼和19名正常人的日眼压波动情况,测量5点,7点,10点,14点,18点,22点的双眼眼压。利用SPSS10.0软件的广义线性模型中的RepeatedMeasures过程进行分析。结果正常眼压性青光眼患者及正常人双眼眼压波动趋势存在显著统计学差异。结论正常眼压性青光眼患者及正常人双眼眼压波动趋势并不完全相同,在科研及临床工作中应将双眼区别对待。Objective To determine if the variations tendency of the diurnal intraocular pressure(IOP)are similar between normal tension glaucoma(NTG)patients and healthy controls. Methods 11 NTG patients and 19 normal individuals were enrolled in the investigation.IOP at 5am,7am,10am,14pm,18pm and 22pm of each participant were measured by Goldmann aplantation tonometer.Data analysis was performed with Repeated Measures of General Linear Model. Results The tendency of the diurnal IOP variations in both NTG patients and normal individuals are different. Conclusions The models of diurnal variations are independent for each eye both in NTG patients and healthy individuals.The effect of a given medicine must be assessed independently for each eye.

关 键 词：青光眼患者 眼压波动 正常人 双眼 不对称性 正常眼压性青光眼 GOLDMANN 抗青光眼药物 广义线性模型 眼压计测量 统计学差异 SPSS 区别对待 临床工作 

分 类 号：R775[医药卫生—眼科] R779.63[医药卫生—临床医学]