躯体焦虑性抑郁症的睡眠脑电图改变  

Change of sleep electroencephalography in depressions with physical anxiety

作　　者：喻东山[1] 赵鹏[1] 徐捷[1] 张心保[1] 侯钢[1] 

机构地区：[1]南京医科大学附属脑科医院,江苏南京210029

出　　处：《临床荟萃》2005年第15期850-852,共3页Clinical Focus

基　　金：南京市跨世纪学科带头人后备人才专项基金资助项目(20028005)

摘　　要：目的探讨躯体焦虑性抑郁症病人的睡眠脑电图改变。方法对6例躯体焦虑性抑郁症(躯体焦虑组)、12例非躯体焦虑性抑郁症(非躯体焦虑组)和10例正常受试者(对照组)检测了睡眠脑电图。结果非躯体焦虑组的快眼动(rapideyemove,REM)活动量、强度和密度均比对照组显著为高[分别为(112±41)%vs(72±18)%;(34±14)%vs(19±4)%,(188±56)%vs(124±19)%,均P<0.05]。躯体焦虑组的REM睡眠时间[(36±20)min]比非躯体焦虑组[(63±22)min]及对照组[(60±17)min]的显著为短(P<0.05)。结论非躯体焦虑性抑郁症病人的REM活动量、强度和密度增加,躯体焦虑性抑郁症的REM睡眠时间缩短。Objective To explore change of sleep electroencephalography in depressions with physical anxiety. Methods Sleep electroencephalography was estimated in 6 depressions with physical anxiety(physical anxiety group), 12 depressions without physical anxiety(non-physical anxiety group) and 10 normal subjects(control group). Results Rapid eye move(REM) activity, intensity and density were significantly higher in non-physical anxiety group than those in control group[(112±41)% vs (72±18)%, (34±14)% vs (19±4)%,(188±56)% vs (124±19)%, respectively, all P < 0.05 ]. REM sleep duration was significantly shorter in physical anxiety group(36±20) min than that in non-physical anxiety group (63±22) min and control group (60±17) min( P < 0.05 ). Conclusion REM activity, intensity and density were increased in depressions without physical anxiety. REM sleep duration was shortened in depression with physical anxiety.

关 键 词：抑郁症 焦虑 多道睡眠描记术 睡眠 快速眼运动 

分 类 号：R749.41[医药卫生—神经病学与精神病学]