涎腺肌上皮瘤中蛋白多糖的电镜组织化学研究  

An electron microscopic histochemical study onproteoglycans in sallvary gland myoepithelioma.

作　　者：王洁[1] 吴奇光[1] 孙开华[1] 贲呈瑞[1] 王晶[1] 朱晓滨[1] 

机构地区：[1]北京医科大学口腔医学院病理研究室,河北医学院口腔病理教研室

出　　处：《中华口腔医学杂志》1995年第4期215-217,共3页Chinese Journal of Stomatology

基　　金：国家自然科学基金

摘　　要：为探讨肌上皮瘤中粘液样区域形成的机理，作者采用钌红电镜组织化学技术观察了４例肌上皮瘤和４例正常腮腺的肌上皮细胞。结果发现，正常腮腺中肌上皮细胞不具有分泌蛋白多糖的功能；而肌上皮瘤细胞能够分泌蛋白多糖，形成粘液样区域。因此提出，在涎腺上皮性肿瘤的病理诊断和鉴别诊断中，应注意到粘液样区域的出现不仅是多形性腺瘤具有的病理特征，也是肌上皮瘤出现的病理变化。Abstract Four myoepitheliomas and four parotid gland werestudied histochemically be electron microscopy afterstain with ruthenium red. It was found that the normalmyoepithelial cells of parotid gland had no secretionfunction, whereas the myoepithelioma cells were capableof secreting proteoglycans and might form the myxoidregion in this tumor. The authors propose that in thepathological diagnosis and differentiat diagnosis of sali-vary gland epithelial tumors, the appearance of themyxoid region is not only the pathological feature ofpleomorphic adenoma, but also the pathological changeof myoepithelioma.

关 键 词：蛋白多糖 电子显微镜 组织化学 涎腺肿瘤 

分 类 号：R739.870.4[医药卫生—肿瘤] R739.870.2[医药卫生—临床医学]