紫外线对纤维蛋白溶解系统活性和血液流变学性质及体外血栓形成的影响  

Influence of Ultraviolet (UV) Irradiation on Fibrinolytic System Activity,Hemorrheology and in Vitro Thrombosis

作　　者：丁立新[1] 杨永辉[1] 张周良[1] 侯瑜[1] 

机构地区：[1]第四军医大学唐都医院康复医学科

出　　处：《中华理疗杂志》1995年第1期3-4,共2页Chinese Journal of Physical Therapy

摘　　要：以全光谱紫外线（ＵＶ）５～１１个生物剂量照射３组健康青年人，①组照射右侧臀部，②组照射左侧前臂屈侧，结果两组照射后血浆纤维蛋白原含量（ＰＦＬ）和优球蛋白溶解时间（ＥＬＴ）均低或短于照射前；③组ＵＶ照射胸前区之前，静脉给予止血芳酸０．１ｇ，照射后ＰＦＬ不再降低。ＵＶ激活纤维蛋白溶解系统（ＦＳ）活性可能与其影响了组织型纤溶酶原激活物（ｔ－ＰＡ）有关。我们并观察到，ＵＶ局部照射皮肤可明显降低脑血栓患者血液粘度，抑制体外血栓形成。healthy subjects, who were the young people,were divided into three groups with UV irradiation (5-11 MED) at different parts (1st group on the right buttock. 2nd on the flexion of left forearm, 3rd on the fore-thoracic part). Then, the plasma fibrinogen level and euglobin lytic time were determined at pre-UV and post-UV irradiation. The comparison was made between the pre-VU and post-UV irradiation. The result showed that the plasma fibrinogen level and euglobin lytic time in the 1st and 2nd group after UV irradiation were lower or shorter.In the 3rd group,before the UV was irradiated, the 0.1g P-aminomethyl benzoic acid was first given. The plasma fibrinogen level hadn't alteration. The effect of UV on the fibrinolytic system activity may be ralated to the plasminogen activator. In addition, The blood viscosity of cerebral thrombosis patients irradiated by UV was reduced and in vitro thromoosis was delayed, too.

关 键 词：紫外线 FS 脑血栓 血液流变学 体外 血栓形成 

分 类 号：R743.330.2[医药卫生—神经病学与精神病学]