城乡队列人群脑卒中发病差异及其影响因素的前瞻性研究  

A Cohort Study on the Difference of Stroke Incidence between Urban and Rural populations and Related Influential Factors

作　　者：杜福昌[1] 王海燕[1] 姚才良 朱杰 王敬良 董璜瑛 邹志芬 张淑莲 钱德音 

机构地区：[1]南京医科大学第一附属医院心血管病研究所,南京医科大学流行病学教研室,南京1014所医院,南京医科大学职工医院,江苏海门心血管病防治办公室

出　　处：《中华流行病学杂志》1995年第5期278-280,共3页Chinese Journal of Epidemiology

基　　金：国家自然科学基金资助课题

摘　　要：在城市７７８名农村１０３１名队列人群中分别进行了为期１５年及１１年的前瞻性观察。城市组脑卒中平均年标化发病率９５．７／１０万，较农村组１８３．１／１０万明显为低。其发病率差异的主要影响因素除年龄外为农村人群的高嗜酒率、高吸烟率、心电图异常及女性收缩压的增高。另外血胆固醇水平偏低也可能为影响农村脑卒中特别是脑出血高发的因素之一。A longitudinal prospective study was carried out in a cohort of 1809 persons aged 35 to 74 at entry, including 778 subjects from urban and 1 031 from rural areas.The average annual age-ad-justed incidence of stroke was 95.7/10￣4 in urban group during a 15-year-period from 1979 to 1994,which was significantly lower than that in rural areas(183.1/10￣4)during a 15-year-period from 1983 to 1994.According to the results through multivariate regression analysis and comparative study of risk factors between urban and rural group at baseline examination,it was suggested that in addition to age,factors as drinking habit, smoking, ECG abnormality and elevated systolic blood pressure(in female)were important parameters causing the difference of incidence between urban and rural groups. Other than those factors mentioned above,low level of serum cholesterol in rural population was also suspected as a possible factor positively influencing the development of stroke.

关 键 词：影响因素 前瞻性观察 中风 发病率 

分 类 号：R743.301[医药卫生—神经病学与精神病学]