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机构地区:[1]福建医学院附属第二医院泌尿外科
出 处:《中华外科杂志》1995年第1期60-61,共2页Chinese Journal of Surgery
摘 要:作者报告9例小儿睾丸内胚窦瘤。患儿年龄7个月~5岁。9例均行经腹股沟根治性患侧睾丸切除术,1例腹膜后转移者加作腹膜后肿块探查活检。4例术后进行了不规则化疗。术后随访1.5~7年,尚健存者5例,均为临床Ⅰ期患者;另4例随访期间死于肿瘤转移。由于内胚窦瘤有合成甲胎蛋白(AFP)的生物学特性,所以测定血清AFP水平对确定肿瘤性质、监视治疗效果有重要意义。作者主张对临床Ⅰ期患者行睾丸切除术加短期化疗,不必常规进行腹膜后淋巴结清除手术。AbstractNine Children with endodermal sinus tumor oftestis have been treated since 1982.Their age rangedfrom 7 months to 5 years. Radical inguinal orchiecto-my was carried out in all the patients. Four patientshave received irregular chemotherapy. The follow-upshowed that 4 died of the metastasis within 5 years and5(stage Ⅰ clinically)survived without evidence of therecurrence for 1.5~7 years after operation. SerumAFP determination may give important information forthe classmcation of the tumor and the evaluation of thefollow-up results, For the cases of clinical stage Ⅰ,radical orchiectomy, short course of chemotherapy,and frequent observations of AFP level are advocated.
分 类 号:R737.210.5[医药卫生—肿瘤] R699.8[医药卫生—临床医学]
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