紫苏子脂肪油的超临界CO_2萃取及GC-MS测定  

Supercritical-C0_2 Fluid Extraction of Fatty Oils of Perilla frutescens Seeds and GC-MS Analysis

作　　者：辉国均 葛发欢[1] 王海波[1] 李菁[1] 梁宝钻[1] 老(彳致)民 吴惠勤[2] 张桂英[2] 

机构地区：[1]广州市医药工业研究所,广州510240 [2]广东省测试分析研究所

出　　处：《中药材》1995年第12期624-625,共2页Journal of Chinese Medicinal Materials

基　　金：国家"八五"攻关项目

摘　　要：用超临界CO_2流体萃取技术从紫苏子中萃取分离出脂肪油,常法甲酯化后,用GC-MS—计算机联用技术对其进行了研究,从中分离鉴定了12个成分,占总脂肪油的99.91％,其中α-亚麻酸为主要成分,占73.46％。棕榈油酸(palmitoleic acid)等8个成分系首次从该植物中分离到。药理毒理证明,该脂肪油具有很好的调血脂作用,无毒副作用。Fatty oils from the seeds of Perilla frutescens were extracted by sup-ercritical-CO_2 fluid (CO2-SFE). The fatty acids were analyzed by GC and GC-MS. The result showed that the fatty acids from CO2-SFE contain 12 components (99.91% of total fattty acids), 8 constituents of them are first obtained from the plant, containing a-linolenic acid 73.46%(main active constituent)and not containing linoleic acid. Pharmo-cological study showed that the fatty oils have signifcant action of lowering blood-lipid and no toxicity.

关 键 词：紫苏子 紫苏油 脂肪酸 超临界萃取 

分 类 号：R282.710.3[医药卫生—中药学] R284[医药卫生—中医学]