血浆前列腺素E_2测定对原发性肝癌的诊断价值  

Diagnostic Value of Assay Plasma Prostaglandin E_2in Primary Cancinoma of the Liver

作　　者：刘占锋[1] 范建高[1] 

机构地区：[1]山东省立医院

出　　处：《肿瘤防治研究》1995年第4期214-215,共2页Cancer Research on Prevention and Treatment

摘　　要：为探讨前列腺素Ｅ＿２（ＰＧＥ＿２）在原发性肝癌（ＰＨＣ）中的应用价值，作者共检测３０例ＰＨＣ（包括转移者２２例、未转移者８例）、１０例酒精性肝病、３９例肝硬化、３０例正常人的血浆ＰＧＥ＿２浓水平。结果表明：ＰＨＣ患者血浆ＰＧＥ＿２水平明显升高（Ｐ＜０．００１），且转移者比未转移者亦明显升高（Ｐ＜０．０１），而两种良性肝病则无明显升高（Ｐ＞０．０５）。提示血浆ＰＧＥ＿２测定对早期发现肝硬化向ＰＨＣ转化，监测ＰＨＣ的扩散及转移有一定意义。To study the vslue of plasma prostaglandin E_2 (PGE2) in primary cancinoma of the liver (PHC), we have determined the level of plasma PGE2 in 30 PHC (including 22 metastasized and 8primary), 10 alcoholic liver disease, 39 cirrhosis, 30 normal persons. The result indicates that the increase of the level of the plasma PGE2 in PHC patients is very significant (P<0. 001), and the increase of metastasized than primary is also significant (P<0. 01), but in the two benign liver diseases the increase is not significant (P>0. 05). We consider that there is some significance in early finding out the changing from ciihosis to PHC and controling the proliferation and transformation of PHC.

关 键 词：肝肿瘤 原发性 诊断 前列腺素E2 测定 

分 类 号：R735.704[医药卫生—肿瘤]