真菌性角膜炎的实验观察与治疗  

Observation and Treatment Of Mycotic Keratitis in Rabbits

作　　者：王香兰[1] 周毅[1] 温守明[1] 金涛[1] 

机构地区：[1]北京市眼科研究所,空军总医院

出　　处：《眼科研究》1995年第3期154-155,共2页Chinese Ophthalmic Research

摘　　要：在兔角膜板层注射镰刀菌，形成深层真菌性角膜炎，病灶向浅层发展形成角膜溃疡。另外，可见虹膜炎、前房积脓、新生血管和卫星病灶，未见角膜穿孔。这些真菌性角膜炎用萘替芬治疗，每天用药５次，共治疗１３天。结果表明萘替芬有一定治疗作用，但与对照组相比差异性不够显著（Ｐ＞０．０５）。abbit corneas were injected intralamellarly with an 20 ul inoculum containing one million spores ofFusarium and deep keratomycosis developed.The infection spread to the superfieial layer and corneal ulcersappeared.Iritis,hypopyon,satellite lesions and vascularization were found.Perforation was not noted.Ex-perimental rabbits with mycotic keratitis were treated with Niftifine.It was given 5 times a day for 13 days.In treated animals the size of corneal ulcer was controlled,but it was not significantly different from the con-trolled group(P>0.05).

关 键 词：真菌性 角膜炎 镰刀菌 萘替芬 药物疗法 

分 类 号：R772.210.5[医药卫生—眼科]