人胚肺细胞转化试验及其对甲基丙烯酸环氧丙酯致癌性的研究  

Human Embryonic Lung Cell Transformation Assay and the Carcinogenecity Research of Glycidyl Methacrylate by Using It

作　　者：肖涛[1] 谢大英[1] 

机构地区：[1]铁道部劳动卫生研究所,中国预防医学科学院劳动卫生与职业病研究所

出　　处：《铁道劳动安全卫生与环保》1995年第4期243-246,共4页Railway Occupational Safety Health & Environmental Protection

摘　　要：建立了人胚肺细胞（２ＢＳ）转化系统，并对甲基丙烯酸环氧丙酯（ＧＭＡ）的潜在致癌性进行了研究。结果表明，转化试验结果良好，试验方法可行。利用２ＢＳ细胞检测ＧＭＡ的转化能力，再次证明了ＧＭＡ对细胞有很强的致转化作用。A neoplastic transformation assay with human embryonic lung cell(2BS)was established and the potential carcinogenecity of Glycidyl Methacrylate(GMA) was studied.The results showed that a good response of transformation was obtained and the method was feasible.GMA was tested for neoplastic transformation activity using 2BS cells in vitro.The results demonstrated again that GMA had strong effect of transformation to the target cells.

关 键 词：人胚肺细胞转化 GMA 致癌性 

分 类 号：R730.231.1[医药卫生—肿瘤]