肝癌、肝硬化、正常肝的AgNOR定量研究  

Quantitative and Comparativestudies of AgNOR in Carcinomatous,Cirrhotic and Normal Livers

作　　者：吴秀红[1] 张其中[1] 陆俐丽[1] 陈钦恭 张德荣[1] 

机构地区：[1]福建省肿瘤医院

出　　处：《实用癌症杂志》1995年第3期156-157,共2页The Practical Journal of Cancer

摘　　要：本文作者应用细胞核仁组成区嗜银蛋白胶银染色技术对６０份肝脏标本进行了完善和比较分析研究。结果表明ＡｇＮｏＲ均数在正常肝、肝硬化及肝瘤三者中有非常显著差异（Ｐ＜０．０１）．作者认为此方法对肝癌诊断、鉴别诊断、分型及预后有重要价值，肝硬化伴不典型增生可能是一种重要的肝癌前期病变。A series of 60 liver biopsy specimens have been investigated quantitatively and comparatively bymeans of AgNOR technique.The results demonstrated that the mean numbers of AgNOR in normal,cirrhoticand carcinomatous livers were significantly different(P<0.01,t=5.87).The authors suggest that thismethod is of great value in diagnosis and differentiating benign and malignant tumor, determining type of tumorand prognosis. Cirrhosis with atypic proliferation may be an important precancerous lesion.

关 键 词：肝肿瘤 肝硬化 AGNOR染色 鉴别诊断 

分 类 号：R735.704[医药卫生—肿瘤] R575.204[医药卫生—临床医学]