视网膜母细胞瘤复发、转移及患儿死亡原因分析  

An Analysis of Causes of Recurrence, Matastasis and Death of Retinoblastoma

作　　者：陈智聪[1] 吴中耀[1] 冯官光[1] 庞友鉴[1] 易玉珍[1] 

机构地区：[1]中山医科大学中山眼科中心

出　　处：《眼科学报》1995年第4期221-223,共3页Eye Science

摘　　要：目的:讨论视网膜母细胞瘤(Rb)复发、转移和病人死亡的原因,并提出在视网膜母细胞瘤诊治中的注意问题。方法:对1967年7月～1992年5月在我中心诊治的Rb病人中复发、转移和死亡的46例进行分析。结果:影响Rb预后的主要因素有:①是否早期诊断。②随着视神经受累程度的增加而死亡率增加。③Rb侵犯眼眶、颅脑和脉络膜。④临床上,Rb继发性青光眼通常伴视神经受累。结论:诊断和治疗的延误导致Rb复发、转移和患者死亡。因此,早期诊断和治疗是提高存活率的关键。眼科学报 1995;11:221—223。Purpose: To discuss the relationship between diagnosis, treatment and recurrence, metastasis, death of Rb patients. Methods: To analyse the data of 46 Rb patients treated in our center from July 1967 to May 1992, who had either recurrence, metastasis or died. Results: The main factors affecting Rb prognosis are: ①early or late diagnosis; ②the mortality rate increased with the degree of optic nerve involvement; ③involvement of orbit, cranial cavity and choroid by Rb; ④clinically?secondary glaucoma often accompanied by optic nerve involvement. Conclusions: Delay in diagnosis and treatment will result in Rb recurrence, metastasis and death. Early diagnosis and treatment is very important for survival rate. Eye Science. 1995; 11: 221 - 223.

关 键 词：眼肿瘤 视网膜母细胞瘤 复发 转移 预后 

分 类 号：R739.72[医药卫生—肿瘤]