恶性肿瘤化疗后及再生障碍性贫血的经验性抗霉菌治疗  

EMPIRICAL ANTIFUNGAL TREATMENT ON MALIGNANT TUMOR AFTER CHEMOTHERAPY AND APLASTIC ANEMIA

作　　者：杨岩[1] 李薇[1] 易永林[1] 李兆华[1] 王娟[1] 张晓霞[1] 

机构地区：[1]白求恩医科大学第一临床学院,吉林省人民医院

出　　处：《白血病》1995年第4期217-219,共3页

摘　　要：总结了急性白血病化疗后２７例，恶性淋巴瘤化疗后５例，横纹肌肉瘤骨髓移植后１例，重型再生障碍性贫血２例，共３５例合并霉菌感染的患者，易导致霉菌感染的６个因素。急性白血病合并霉菌感染组与合并细菌感染组相比较，对每一常见临床资料经统计学分析后予以一积分数值，并回顾性比较了两组积分分布状态。在此基础上提出：总积分大于或等于１１就应进行抗霉菌治疗；总积分８～１０之间，应进行试验性抗霉菌治疗。We analysed 3 5 cases of fungal infection from January 1 992 to April 1 994.These casesinclude 2 7 cases of acute leukemia after chemotherapy, 5 cases of malignant lymphoma afterchemotherapy,1 cases of rhabdomyosarcoma after bone marrow transplantation,and 2 cases ofsevere-type aplastic anemia.We summarized 6 kinds of fungal-infective factors,and took thosecomplicating bacteral and viral infection as control.We analysed acute leukemia with fungalinfection and integrate each common item statistically,then compared the integration of the twogroups retrospectively. According to the analysis,antifungal treatment should be given if thetotal integration is more than 11,while experimental antifungal treatment should be given if thetotal integration is more than 8 and less than 10.

关 键 词：白血病 淋巴瘤 再生障碍贫血 霉菌感染 治疗 

分 类 号：R733.7[医药卫生—肿瘤] R556.505[医药卫生—临床医学]