吗丁啉治疗小儿厌食症  

Treatment of children's anorexia with domperidone

作　　者：方鹤松[1] 王玉坤[1] 陈箐[1] 王俊侠[1] 刘庆伟[1] 胡亚美[1] 江载芳[1] 闫春梅[1] 张淑华[1] 邓文碧[1] 段恕诚[1] 邵彩虹[1] 吴实[1] 何莫 鲍一笑[1] 章沛时[1] 赵禅文 唐泽媛[1] 李炜红 

机构地区：[1]首都儿科研究所,北京儿童医院,上海医科大学儿科医院,湖南省儿童医院,华西医科大学附属医院儿科

出　　处：《北京医学》1995年第2期85-88,共4页Beijing Medical Journal

摘　　要：１９９１年７～１２月，采用新型胃动力药吗丁啉液剂（西安杨森制药有限公司出品）口服，治疗小儿厌食症３５８例，并设胃酶合剂对照组９５例。厌食病程最短２周，最长１３．５年。经吗丁啉治疗４周后，６４．８％于１周内食欲好转，食量恢复到正常者占４２．３％，恢复到正常的３／４者占３４．７％，６６．５％表现体重增加。总有效率为８４．６％，其中痊愈率３６．０％，显效２７．８％，有效２０．７％，无效１５．４％，显著优于对照组。Three hundred and fifty eight cases of children's anorexia were treated with domperidone from July through December 1991. 95 cases as control group treated with mixture pepsin. The course of anorexia lasted from 2 weeks to 13.5 years, After treatment with domperidone for 4 weeks, appetite was improved in 64.8%of the cases within one week; 42.3% of the cases recovered their normal capacity of eating, and 34.7%to 3/4 of the normal appetite, Body weight gain was seen in 66.5%of the cases. The recovery rate, significantly effective rate and the effective rate were 36.0%,27.8%and 20.7%respectively and the total effective rate was 84.6%. 15.4%of the cases showed no improvement. This study showed that, treatment with domperidone gave better results than that with mixture pepsin. Treatment of children' s anorexia with domperidone was proved to be simple, convenient, highly effective and without any side effect.

关 键 词：吗丁啉 厌食症 药物疗法 儿童 

分 类 号：R573.5[医药卫生—消化系统] R442.1[医药卫生—内科学]