原发性慢性进展型多发性硬化（附八例临床观察）  

Primary chronic progressive multiple sclerosis clinical observation of 8 cases

作　　者：杨荫昌[1] 邵杰[1] 白颖 黄蕙芬[1] 赵葆洵[1] 

机构地区：[1]中国医学科学院北京协和医院神经科

出　　处：《北京医学》1995年第3期129-132,共4页Beijing Medical Journal

摘　　要：本文分析了８例原发性慢性进展型多发性硬化（ＰＣＰＭＳ），具有发病年龄较晚，男性比例较高；视神经炎较少，中枢损害较多；脑脊液炎性改变较少，ＣＴ、ＭＲＩ及诱发电位的阳性率较高；皮质类固醇疗效较差以及近期预后较好、远期预后较差等临床特征。指出ＰＣＰＭＳ是多发性硬化的一个特殊的、独立的临床类型。Eight cases of primary chronic progressive multiple sclerosis(PCPMS)were analysed. Their clinical features were as follows : onset at later age;more male patients been affected than female patients; central nervous system was more frequently involved, while optic neuritis was less frequently involved; there were less inflammatory changes in the cerebrospinal fluid,higher possitive findings on examinations of CT, MRI and evoked potentials. Treatment with steroids was less effective, Near prognosis was better than late prognosis. It indicated that PCPMS is a special and separated clinical pattern of multiple sclerosis.

关 键 词：多发性硬化症 类型 症状 PCPMS 病例分析 

分 类 号：R744.51[医药卫生—神经病学与精神病学]