急性心肌缺血时血小板数量和容积变化关系的分析  

Analysis of Relationship Between Count and Volume of Platelet During Early Myocardial Ischemia

作　　者：赵志青[1] 李艳[2] 裴其应[2] 牛国保[1] 王跃民[1] 减益民 

机构地区：[1]第四军医大学生理学教研室 [2]西京医院检验科

出　　处：《第四军医大学学报》1989年第1期23-25,共3页Journal of the Fourth Military Medical University

摘　　要：在麻醉开胸狗,观察了阻断冠脉后血小板数量(PC)和平均血小扳容积(MPV)的变化。结果如下:急性心肌缺血早期,两者呈非线件反方向变化,PC减少,MPV增加(P>0.05);而由PC和MPV计算的衍生指标,血小板临界容积(Platelet-crit, PCT)则和PC改变呈良好相关性,PC减少,PCT也降低(P<0.01)。这些结果表明,心肌缺血时PC和MPV发生明显异常变化,PCT改变有助于证实这一点。Changes of platelet count (PC) and mean platelet volume (MPV) were observed in anesthetized open-chest dogs after coronary occlusion. Results were as follows: There was an inverse, nonlinear relationship between PC and MPV, with no statistical difference (P>0.05) during early myocardial ischemia. However, a direct, linear relationship was suggested between platelet-crit (PCT) calculated by PC and MPV, and PC, with significant statistical difference (p<0.01). These results show that changes in PC and MPV during myocardial ischemia are obviously abnormal, and change in PCT is helpful to prove this phenomenon.

关 键 词：血小板 心肌缺血 冠心病 

分 类 号：R331.143[医药卫生—人体生理学]