武汉地区汉族人群补体第二成分(C2)的遗传多态现象  

Genetic Polymorphism of the Second Component of Human Complement (C2) in the Han Nationality in Wuhan District of China

作　　者：田延武[1] 赵修竹[1] 

机构地区：[1]同济医科大学病理生理学教研室

出　　处：《Acta Genetica Sinica》1989年第3期226-229,共4页

基　　金：国家自然科学基金

摘　　要：使用聚丙烯酰胺凝胶等电聚焦溶血覆盖技术,调查了武汉地区231例汉族人的C2多态现象。C2表型为C2C的216人,C2BC9人,C2AC5人,C2A1人。基因频率为:C2~*A 0.0151,C2~*B 0.0195, C2~*C 0.9654。A total number of 231 unrelated Chinese (Han Nationality) were investigated for C2 polymorphism by hemolytic overlay technique after polyacrylamide gel isoelectric focusing on plasmas.The following phenctype distributions were observed:C2C,216; C2BC,9; C2AC,5; and C2A,1.The gene frequencies calculated from these phenotypes were as follows:C2*A,0.015; C2*B,0.019; C2*C,0.965.The C2 phenotypic frequency distributions were in agreement with those expected from Hardy-Weinberg equilibrium.

关 键 词：补体第二成分 遗传多态现象 

分 类 号：Q346.5[生物学—遗传学]