肝癌介入治疗中预后因素的分析  

Analysis of prognostic factors in hepatocellular carcinoma treated by interventional radiological therapy

作　　者：贾雨辰[1] 刘崎[1] 贺佳[1] 王振堂[1] 陈栋[1] 孙飞[1] 田建明[1] 

机构地区：[1]第二军医大学长海医院放射科,上海第二军医大学长海医院医学统计教研室

出　　处：《肝胆外科杂志》1995年第3期143-146,共4页Journal of Hepatobiliary Surgery

摘　　要：自１９８７年１月至１９９２年１２月．我院经介入治疗的６２１例晚期肝癌，应用Ｃｏｘ比例风险模型进行了回顾性分析，其结果如下。影响预后最明显的因素是肿瘤大小、门脉内癌栓、治疗方法和治疗次数。６２１例总的生存率，１、３、５年分别为６２．２３％，１２．８５％和７．４５％，中位生存期是１６．２３月。我们的资料揭示ＬｐＧｓＴＡＣＥ复合治疗是最有效的方法。了解肝癌的预后因素，对选择与处理病人是有益的。Using the Cox's proportional hazard model. We retrospectively and statistically analysed 621 cases of unresectable late hepatic carcinoma treated with transcatheter arterial embolization or infusion, during the perod from 1986 to 1992.The results were as follows:the most significant prognostic factors were tumor size,tumor embolus in the portal vein, modality of treatment and number of treatment. The overall commulative survival rates for 1-. 3-. and 5- year were 62. 23%. 12. 85% and 7. 45 % respectively. The median duration of survival was 16. 23 months. Our findings suggested that conbination therapy (LpGsTACE) is the best modality for treatment of hepatocelluar carcinoma. Furthermore. knowedge of the prognostic factors is useful for the selection and management of patients.

关 键 词：肝癌 介入疗法 预后 影响因素 

分 类 号：R735.705[医药卫生—肿瘤]