3,5-环-6-甲氧基-孕甾-20(22)-烯立体选择性硼氢化反应的研究  

STUDY ON STEROSELECTIVE BOROHYDROGENATION OF 3,5-CYCLO-6-METHOXYL-PREGN-20(22)-ENE

作　　者：刘兴平[1] 梁晓天[2] 

机构地区：[1]兰州大学有机化学研究所 [2]中国医学科学院药物研究所

出　　处：《应用化学》1989年第2期60-62,共3页Chinese Journal of Applied Chemistry

摘　　要：3,5-环-6-甲氧基-孕甾-20S-22-醇1 是合成2的前体,而后者是合成高效植物激素油菜甾醇内酯3及其类似物的关键中间体.The stereoselective borohydrogenation of 3, 5-cyclo-6-methoxyl-pregn-20(22) 5 by dicy-clohexylboronane to 20S-22-ol 1 was investigated .An appropriate ratio of sodium borohydrideto boron trifluoride used in this reaction was given, and the structure of 3 unexpected pro-ducts 6,7,8 obtained in this reaction was determined.

关 键 词：立体选择性硼氢化反应 二环已基硼烷 硼氢化钠 三氟化硼 油菜甾醇内酯 

分 类 号：O629.23[理学—有机化学]