Cu(Ⅱ)-氨基酸-核苷酸三元配合物——Ⅱ.Cu(Ⅱ)—L-组氨酸、L-赖氨酸-5′-嘌呤核苷酸三元配合物  

Ternary Complexes of Copper(Ⅱ) with Amino Acid and Nucleotide——Ⅱ. Copper(Ⅱ) with L-His or L-Lys and 5'-Purine Nucleotide

作　　者：邵昌平[1] 赵丽华[1] 刘宇新[1] 郭和夫[1] 

机构地区：[1]中国科学院大连化学物理研究所,大连116023

出　　处：《化学学报》1995年第8期769-774,共6页Acta Chimica Sinica

摘　　要：合成和表征了新的三元配合物:[Cu(L-His)(5′-AMP)]Cl_2·4H_2O,[Cu(L-His)(5′-GMP)]Cl_2,[Cu(L-His)(5′-IMP)]Cl_2·2H_2O,[Cu(L-Lys)_2(5′-GMP)]Cl_2·6H_2O,Na_2[Cu(L-Lys)_2(5′-GMPH_(-2)]·6H_2O,Na_2[Cu(L-Lys)_2(5′GTP_(-2))]·6H_2O,Na_2[Cu(L-Lsy)_2(5′-IMPH_(-2))]·10H_2O.IR及NMR谱表明,5′-嘌呤核苷酸以嘌呤碱基上的7-N原子与Cu(Ⅱ)配位.在5′-嘌呤核苷酸形成的配合物中,磷酸根不参与配位,但是Na_2·5′-GMPH_(-2)和Na_2·5′-GTPH_(-2)的磷酸根参与配位,而Na_2·5′-IMPH_(-2)的磷酸根不参与配位.The ternary complexes of copper(Ⅱ) with amino acid(L-His and L-Lys) and nucleotide (5'-purine nucleotide and its salt of sodium) were first synthesized and characterized by elemental, conductivity, IR, 1H NMR and 13C NMR spectra. In the ternary complexes, the purine base coordinates with copper(Ⅱ) through the 7-N atom. The phosphate group of 5'-nucleotide in the ternary complexes does not coordinate with copper(Ⅱ). When the nucleotide takes part in the reaction in the form of Na2·5'-GMPH-2 and Na2·5'-GTPH-2, the phosphate group may be coordinate with copper(Ⅱ) in the ternary complexes, but not for Na2·5/-IMPH-2.

关 键 词：配合物 氨基酸 嘌呤核苷酸 组氨酸 铜 

分 类 号：O614.121[理学—无机化学]