氢过氧化物酶(HPO)阳性Phi小体形态特点、超微细胞化学观察及其临床意义  

AN OBSERVATION ON MORPHOLOGIC FEATURES AND ULTRAMIGRO-CYTOCHEMICAL STRUCTURES OF HYDROPROXIDASE (HPO)POSITIVE PHI BODIES AND ITS CLINICAL SIGNFICANCE

作　　者：沙滨 夏薇 孙敏 崔新宇 宁嗣宗 李永华 

机构地区：[1]吉林医学院血液检验教研室 [2]吉林中西医结合医院

出　　处：《吉林医学院学报》1995年第2期13-16,共4页

摘　　要：本文对４１例成人白血病及４例骨髓增生异常综合征（ＭＤＳ）病人的骨髓标本进行氢过氧化物酶（ＨＰＯ）染色，观察ＨＰＯ阳性Ｐｈｉ小体在光镜下的形态特点及电镜下细胞化学超微结构，并初步探讨了ＨＰＯ染色技术及Ｐｈｉ小体检测的临床意义。作者认为：该染色法特异性强，重复性好，操作简便，对于活动性ＡＭＬ的诊断几无假阳性，并可用于指导治疗，值得推广应用。Bone marrow smears from 41 patients with adult leukemia and 4 with myelodysplastic syndrome (MDS)were stained by hydroperoxidase (HPO) staining technique.The morphologic features and ultrami-cro- cytochemical structures were observed under light and electron microscopes respectively. Hydroperoxidase staining method and the significance of Phi bodies detection were also preliminarily investigated. It is thought that the method possesses the advantages of stronger spesificity, better reproducibility, simple operation and almost no false positive rate for diagnosing active acute myeloid leukemia , and may be used for directing treatment , being worthy to popularize.

关 键 词：氢过氧化物酶 形态学 Phi小体 白血病 诊断 

分 类 号：R733.710.4[医药卫生—肿瘤]