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机构地区:[1]第二军医大学长海医院消化内科,上海200433
出 处:《第二军医大学学报》2005年第8期863-864,共2页Academic Journal of Second Military Medical University
基 金:国家自然科学基金(30270504).
摘 要:目的:研究老年重症急性胰腺炎(SAP)的临床诊治特点。方法:对78例老年(55~84岁)SAP患者进行回顾性分析,并与同期107例非老年(22~54岁)对照组SAP患者资料进行对比研究。结果:老年SAP患者以胆石症为主要病因,多伴其他慢性疾病,高血压最多见。老年患者各种临床症状发生率均低于对照组(P<0.05);老年组APACHEⅡ(24、48h)和Ranson评分高于对照组(P<0.05);老年患者的局部并发症和多器官功能障碍(衰竭)发生率明显高于对照组(P<0.05),病死率和死亡原因与对照组无明显差异。结论:我国老年SAP病因以胆源性为主,临床症状无特异性,伴发疾病多,并发症发生率相对较高,诊断与治疗难度较大。Objective:To study the clinical features of severe acute pancreatitis(SAP) in aged patients. Methods: The clinical data of 78 aged patients(55-84 years old) with SAP were analyzed and compared with those of 107 young SAP patients(22-54 years old) hospitalized in our hospital over the past 10 years. Results: Most aged patients were associated either with gall stones or idiopathy and chronic diseases, especially hypertension. The incidences of all kinds of clinical symtoms in aged SAP patients were lower than those of the yound SAP patients (P〈0.05). APACHE Ⅱ (24、48 h) and Ranson scores of aged SAP patients were higher than those of the control group(P〈0.05). The incidences of local complications and multiple organ dysfunction syndrome of aged cases were obvious higher than those of the control group(P〈0. 05). There was no significant difference in mortality and cause of death between the 2 groups. Conclusion: In China, gall stone is the most common cause of SAP which lacks characteristic clinical symptoms and is often with complications, making diagnosis and treatment difficult.
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