cTnI测定在急性脑心综合征中的意义  

Study of clinical significance of Cardiac troponin-I(cTnI) in brain-heart syndrome

作　　者：银广悦[1] 丁俊丽[2] 孙志华[2] 吴宝水[2] 黄益兴[2] 

机构地区：[1]中国石油天然气集团公司中心医院检验科,河北廓坊065000 [2]中国石油天然气集团公司中心医院神经内科,河北廓坊065000

出　　处：《脑与神经疾病杂志》2005年第4期262-263,275,共3页Journal of Brain and Nervous Diseases

摘　　要：目的:探讨心肌肌钙蛋白I(cTnI)测定在急性脑心综合征中的意义。方法:对37例血清相关酶谱增高的急性脑梗死患者并设对照组进行cTnI测定,对各组结果进行对照分析。结果:急性脑梗死合并急性心肌梗死患者13例,cTnI水平测定为2.631±1.235ng/ml,与正常对照组(cTnI测定为0.022±0.014ng/ml)有非常显著差异P<0.001)。脑心综合征(脑心反应组)24例,cTnI水平测定为0.033±0.021ng/ml,与正常对照组无显著差异(P>0.05)。脑梗死合并心肌梗死组cTnI与脑心综合征组比较有显著差异(P<0.05)。结论:cTnI测定可以对急性脑梗死患者血清相关酶谱增高的原因(有无心肌梗死)进行鉴别。Objectives： To observe the clinical significance of Cardiac troponin-I（cTnI） in brain-heart syndrome . Methods： To detect the cTnI of 37 patients with acute cerebral infarction （ACI） whose serum enzyms were higher than normal and compare with that in the normal control group, Results： There were 13 patients with ACI and acute myocardia infarction（AMI）,whose cTnI＇s Level were 2. 631±1. 235ng/ml,the difference of cTnI was very remarkable betwteen ACI ＋AMI group and the normal control group whose cTnI＇s level were 0.022±0.014ng/ml（P〈0.001）. There were 24 patients with brain-heart syndrome（brain-heart reaction） whose cTnI＇s level were 0. 033 ± 0. 021ng/ml, there were no remarkable difference between the brtdn-heart syndrome group and the normal control group（ P〉0.05 ）. There were remarkable difference between ACI ＋ AMI group and the brain heart syndrome group（P〈0.05）. Conclusions： Detecting the cInI could help us to distinguish what cause the serum enzyms go up（AMI or not）.

关 键 词：急性脑梗死 急性心肌梗死 心肌肌钙蛋白I 

分 类 号：R747.9[医药卫生—神经病学与精神病学]