鼻神经内分泌癌的诊断和治疗(附5例报告)  

作　　者：俞杰 王凯 沈志森 李幼珍 

机构地区：[1]浙江省宁波市李惠利医院,315041

出　　处：《浙江临床医学》2005年第8期805-806,共2页Zhejiang Clinical Medical Journal

摘　　要：目的研究鼻神经内分泌癌的诊断和治疗,探讨其预后。方法对5例鼻神经内分泌癌作临床分析,其中,左侧2例,右侧3例;平均病程8.7个月,病变范围广泛或局限。单纯手术1例,化疗和放疗2例,综合治疗2例。结果经组织病理学检查和免疫组化确诊为鼻神经内分泌癌,其中小细胞型4例,未分化型1例,1例1年8个月死亡,1例1年后死亡;2例随访,1例仍在治疗随访中。结论本病临床治疗应采用综合治疗方案,预后与病变范围及病理类型有关。Objective To study diagnosis, therapy of nasal neuroendocrine carcinoma （NEC） and discus the factor related with prognosis.Methods 5 cases of nasal neuroendocrine carcinoma were analysed. 1 case by ouly operation, 2 cases by radiotherapy and chemotherapy, 2 cases by combined treatment. Results All neuroendocrine carcinomas cases were confirmed by pathology and immunohistochemistry. 4 cases were Parvocellular earcinoma, 1 case was undifferentiated carcinoma. One patient died in 20 months and One died in 12 months after treatment. Two patients were followingup, one was still in treatment. Conclusion Combined treatment should be adopted to neuroendocrine carcinoma, the prognosis is related with the lesion extent and pathological types.

关 键 词：鼻 神经内分泌癌 病变范围 鼻神经内分泌癌 诊断和治疗 综合治疗方案 组织病理学检查 治疗随访 临床分析 单纯手术 

分 类 号：R739.62[医药卫生—肿瘤]