肠癌患者心理健康和家庭社会功能与生活质量的多因素分析  

Multivariate analysis of psychological health, family and social function in quality of life in patients with intestinal cancer

作　　者：何小梅[1] 付饶[1] 黄玉清[1] 肖红英[1] 冯爽[2] 

机构地区：[1]四川省肿瘤医院急诊科,四川省成都市610041 [2]西南科技大学通讯系,四川省绵阳市621002

出　　处：《中国临床康复》2005年第28期80-82,共3页Chinese Journal of Clinical Rehabilitation

基　　金：四川省应用基础研究项目基金(01SY051-46)~~

摘　　要：目的:探讨肠癌患者的生活质量情况及其影响因素。方法:选择2001-01/2002-07四川省肿瘤医院及四川大学华西医科大学附属医院确诊的肠癌患者为调查对象。编制符合中国国情的肠癌患者的生活质量评价量表,采用面访问卷方法进行调查。内容包括:①一般人口学特征。②疾病及治疗情况。③生活质量情况。生活质量情况参照癌症患者生活质量测定量表(EORTC-QLQ-30)设计,内容包括日常躯体功能,心理健康状态,家庭社会功能,一般症状与副反应以及自我生活质量评价5个主要测量维度,并增加肠癌特殊副反应条目,生活质量所有相关条目共计42项。每个条目取值0～10分,各条目得分越高生活质量越好。采用特尔菲法为各测量条目附权重,各测量维度及总分计算方法为:分值=条目得分×权重×10。生命质量总分=日常躯体功能评分+心理健康评分+家庭社会功能评分+一般症状副反应评分+特殊副反应评分+自我总评价评分。采用多元线性回归模型分析影响患者生活质量的因素。结果:发放问卷94份,收回合格问卷94份,有效率100%。①生活质量权重及各测量维度评分情况:肠癌患者生活质量评分总评分为58.16±15.7。日常躯体功能、心理健康、社会家庭功能、一般症状及副反应、特殊副反应、自我生活质量评价的评分分别是9.75±3.16,14.09±4.44,10.84±3.48,8.50±2.50,11.64±4.81,4.01±1.42。权重值分别是0.161,0.237、0.189,0.128,0.21,0.075。单条目评分时经济发生困难(归属家庭社会功能)、害怕疾病转移(归属心理健康)、体育锻炼(归属日常躯体功能)评分较低。②不同肠癌患者生活质量评分比较:转移性肠癌、直肠癌、结肠癌患者生活质量总评分分别是65.53±9.04,52.03±16.17,64.28±17.13,差异有显著性(F=5.883,P<0.05)。③生活质量的多因素分析:肠癌患者的治疗后特殊副反应与生活质量评分呈正相关。线性回�AIM： To study the quality of life in patients with intestinal cancer, and discuss the influencing factors. METHODS： From January 2001 to July 2002, 94 patients with intestinal cancer were investigated with questionnaire of quality of life for intestines cancer. Quality of life items were designed according to EORTC QLQ-30, and physical function, psychological health, family and social function, symptom and side effect, self-evaluation and special side effects for intestines cancer were included. The score of each item range is from 0 to 10. The score of items is higher the quality of life is better. The global score and sub-dimensional score equal to sum of score of each item weight ×10, while weight of each item was generated with Delphi method. The related factors for quality of life were analyzed with the multivariate linear regression. RESULTS： 94 questionnaires were sent out, and all were collected back, the response rate was 100%. ① The quality of life total score of the patients with intestinal cancer was 58.16±15.7, The scores of physical function, psychological health, family and social function, symptom and side effect, special side effects and self-evaluation were 9.75±3.16, 14.09±4.44, 10.84±3.48, 8.50±2.50, 11.64±4.81, 4.01±1.42, and the weights were 0.161, 0.237, 0.189, 0.128, 0.21, 0.075. ② The total scores of quality of life in the patients with transferring intestinal cancer, rectal cancer and colon cancer respectively were 65.53±9.04, 52.03±16.17, 64.28±17.13, there were significant differences （F=5.883, P 〈 0.05）. ③ The results of linear regression showed that the factor “suffering from mental injury in two weeks” was.negatively correlated with the total score and all sub-dimensional score. The high medical insurance was positively correlated with the score of the total score, self-evaluation, physical function and psychological health. Diagnostic period was positively correlated with physical function. High monthly income was positively correlated with social a

关 键 词：生活质量 消化系统肿瘤 回归分析 

分 类 号：R574[医药卫生—消化系统]