晚发与非晚发精神分裂症临床对照分析  

A clinical comparison of late-onset vs non-late-onset schizophrenia.

作　　者：王年生[1] 龚传鹏 赵海英 郑华胜 徐汉明 李志成[1] 王健[1] 张玉琦[1] 初建峰[1] 刘庆海[1] 吕兴善[1] 林炎 欧文前 刘福生 

机构地区：[1]山东省济宁市精神病防治院,湖北省武汉市精神病医院,山东省聊城地区精神病院,福建省福州神经精神病防治院

出　　处：《临床精神医学杂志》1995年第5期274-276,共3页Journal of Clinical Psychiatry

摘　　要：对４所精神病院较近期入院、初次发病年龄在４５岁以上的晚发性精神分裂症患者共２２８例进行观察，以同期住院的４５岁以下、初次发病的精神分裂患者３０９例为对照。结果发现，晚发组文化程度较低，发病前有精神或躯体因素为诱因者较多见，以急性或亚急性起病较多，早期症状以神经症样症状较多见，而入格改变较少见，临床类型以偏执型为多，近期疗效较好。临床症状中有不少项目两组患者也有显著差别，除发病年龄两组间又存在这些显著差异，因此考虑两组是否存在有异质性的可能。AbstractObjective: To detect the differences between late-onset and non-lateonset schizophrenia. Method:Two hundred and twenty-eight late-onset (>45 years old)schizophrenic patients from 4 mental hospi-tals were compared with 309 non-late-onset schizophrenic inpatients admitted during the same period inthe same hospitals,Result:It showed that late-onset patients had lower educational level,more psycho-logical or physical precipitating factors,more acute ot subacute onset,more neurotic symptoms,lesspersonality change,more frequently paranoid in nature,and a better short-term response to treatment.Discussion:The authors suggested that these findings attested to the heterogeneity of the schizophrenia.

关 键 词：精神分裂症 晚发性 临床对照分析 

分 类 号：R749.3[医药卫生—神经病学与精神病学]