吸烟对消化性溃疡影响的研究  

INFLUENCE OF SMOKING ON PEPTIC ULCER

作　　者：陈传福[1] 李鹤亭[1] 邵茂亭 许春华[1] 侯云修[1] 牟卫平[1] 孙经武[1] 朱培华[1] 项在栋 

机构地区：[1]滨州医学院附属医院消化内科

出　　处：《内镜》1995年第5期275-277,共3页

摘　　要：本组选择经胃镜检查确诊的８０例消化性溃疡均为吸烟者。应用甲氰咪胍治疗３个月，在治疗期间均劝患者戒烟，结果又分为吸烟组和戒烟组。在３个月和６个月时分别复查胃镜检查，在３个月时５４例溃疡愈合，占７３％；吸烟组和戒烟组未愈合之溃疡的百分数相比没有显著差异。然而在６个月时，吸烟组与戒烟组未愈合之溃疡百分比有显著差异（６０％比２３％，Ｐ＜０．０５）。Eighty cigarette smoking patients with peptic ulcer diagnosed by endoscopy were studied.All the patients were advised to stop smoking and received a three-month course of cimetidine treatment,and then they were divided into two groups:patients who continued smoking and stopped smoking.Endoscopy was repeated after three months(n=74)and six months(n=64)respectively.After 3 months, treatment ulcer healing`was found in 54 patients(73%)and there was no significant difference between smoking and patients who had stopped smoking. After 6 months,however,the proportion(60%) of peptic ulcer was higher in smoking patients than(23%)ex-smokers(P<0.05).We consider that persistent smoking does not obviously affect the healing effect of cimetidine on peptic ulcer,but can prolong the duration of peptic ulcer after stopping cimetidine treatment.

关 键 词：吸烟 消化性溃疡 甲氰咪胍 

分 类 号：R570.5[医药卫生—消化系统] R163[医药卫生—内科学]