湘西间日疟潜伏期与复发的实验观察  

EXPERIMENTAL STUDIES ON THE INCUBATION PERIOD AND RELAPSE PATTERNS IN VIVAX MALARIA IN WEST HUNAN

作　　者：王子敏 何元珍 黄峥 李庆俊 唐来仪 张湘君 庞禄林 杨柏林[3] 王文俊[3] 

机构地区：[1]湖南省怀化地区卫生防疫站 [2]湖南省卫生防疫站 [3]中国预防医学科学院寄生虫病研究所

出　　处：《中国寄生虫学与寄生虫病杂志》1989年第3期181-183,共3页Chinese Journal of Parasitology and Parasitic Diseases

摘　　要：1985年9月至1987年10月,对从湖南省西部慈利县自然感染者分离的间日疟原虫,连续蚊传5代的27例病例,以氯喹1.5g(基质)3d疗法治疗。治疗后,13例短潜伏期(平均17.2d)病例的复发率为100%,第2～4次的复发率依次为76.9、62.5和20.0%;14例长潜伏期(平均287.2d)的复发率66.7％,第2次的复发率为37.5%,未见第3次复发。这两类间日疟复发类型的差异,主要表现于第1潜隐期,即潜伏期短者第1潜隐期长(平均243.4d),而潜伏期长者则第1潜隐期短(平均55.3d)。The paper reports on some biological characteristics of Plasmodium vivax isolated from Cili County of Hunan Province.27 volunteers inoculated with sporozoites were observed for 1.5 to 2 years. Treat-ment with chloroquine 1.5g base for 3 days was initiated on tne first day of tne pri mary attack and of each relapse.The data indicate that tne first latent period in 13 cases developing malaria after short incubation period is very long, being 243.4 (191-297) days; however it is always short, being 55.3 (51-80) days in 14 patients with long incubation period. Definite relationship existing between incubation period and relapse patterns in vivax malaria is thus demonstrated.

关 键 词：间日疟 疟疾 潜伏 复发 

分 类 号：R531.3[医药卫生—内科学]