视网膜电图a波的光强－反应函数研究  

Study on the Scotopic Intensity-Response Function of the a-wave of the Eletroretinogram

作　　者：范先群[1] 奚渭清[1] 李海生[1] 王仁緅[1] 张芸芸[1] 

机构地区：[1]上海第二医科大学附属第九人民医院眼科

出　　处：《上海第二医科大学学报》1995年第2期105-109,共5页Acta Universitatis Medicinalis Secondae Shanghai

摘　　要：采用系列强度的刺激闪光记录２０例３０只正常眼的暗适应视网膜电图（ＥＲＧ），应用频谱分析方法，探讨ＥＲＧａ波的光强－反应函数。结果表明，在约２个对数单位范围，ＥＲＧａ波为双谷ａ波，系振荡电位第１子波（ＯＰ＿１）叠加于ａ波所致。临床测量双谷ａ波ＥＲＧ时，先用频谱分析方法消除ＯＰ＿１对ａ的分割，测量单谷ａ波的峰时和振幅。暗适应ＥＲＧａ波的光强－反应关系曲线为“Ｓ”型，符合Ｎａｋａ－Ｒｕｓｈｔｏｎ等式：Ｒ／Ｒｍａｘ＝Ｉ￣ｎ（Ｉ￣ｎ＋Ｋ￣ｎ），其中有三个独立参数：Ｒｍａｘ，Ｋ，ｎ。Scotopic a-wave intensity-response functions were studied in 30 normal-eye of 20 subjects. For a middle range of luminances,the a-wave appeared in a double-trough shape: the a1-wave and the a2-wave. The presence of the double-trough a-wave is due to the first oscillatory potential(OP1)which overrides on the a-wave and splits the a-wave into the double-trough a-wave. The double-trough a-wave became the single-trough a-wave when the OP1 was removed from the double-trough a-wave by frequence-domam analysis. The intensity-response function of the a-wave of the dark adapted electroretinogram accords with the Naka-Rushton equation: R/Rmax=I￣n/(I￣n+K￣n), which has three independent parameters:the maximum response(Rmax),Slope(n)and half saturation constant(K).

关 键 词：视网膜电图 A波 光强-反应函数 频谱分析 

分 类 号：R770.43[医药卫生—眼科]