一例^(60)Co急性事故受照者染色体畸变分析及连续随访  

A CASE OF CHROMOSOME ABERRATIONS IN FOLLOWING AN ACCIDENTAL EXPOSURE TO ~ (60)Co γ-RAYS

作　　者：邵松生[1] 冯嘉林[1] 邹美君 刘红珍 林雅萍 

机构地区：[1]上海医科大学放射医学研究所

出　　处：《上海医科大学学报》1995年第2期127-129,共3页Journal of Fudan University(Medical Science)

摘　　要：一例６０Ｃｏγ给意外事故受照者于照后２．５ ｈ检查淋巴细胞染色体，双着丝粒加环 的频率为 ８９％，估算受照剂量为 ４． ７８（４．５３～４． ８８） Ｇｙ。以后的１２ａ检查中，上述畸变呈对数 回归下降，而稳定性畸变保持不变，并有上升趋势。照后早期的剂量估算以双着丝粒加环为主， 照后晚期效应的研究应检查稳定性畸变。The chromosomes of peripheral blood lymphocytes were examined in a case of 60Co γ-rays exposure accident 2.5h later. The frequeney of dicentrics plus centric rings (Dic+R) was 89%, and radiation dose of 4.78 (4.53-4.88) Gy was estimated. Lymphocyte chromosome aberrations were examined in the following 12 years. The incidences of Dic+R reduced with logarithmic regression(r= -0. 989 5), while the number of cells with stable aberrations remained unchanged and showing a tendency to increase. It was suggested that for estimation of radiation dose a few hours after exposure the % of Dic+R was useful, but for study of late effect the stable aberrations was indisponsable.

关 键 词：染色体畸变 稳定性畸变 钴60 辐射 受照者 

分 类 号：R818.71X59[医药卫生—放射医学]