前列腺癌AgNOR定量研究  

QuantitativeStudyofAgNORinProstaticCarcinoma

作　　者：杨亚龙[1] 赵星裕 杨抚华[1] 

机构地区：[1]山海丹集团研究部,华西医科大学

出　　处：《实用癌症杂志》1995年第2期86-87,共2页The Practical Journal of Cancer

摘　　要：采用自动图像分析术定量观察前列腺组织和癌的ＡｇＮＯＲ。结果：前列腺癌（２７例）为４．６５±０．６８，前列腺增生（１９例）为２．４１±０．２６，正常成人前列腺（４例）为１．３７±０．１３，正常胎儿前列腺（５例）为３．４３±０．９６；四者间比较有显著差异。前列腺癌ＡｇＮｏＲ颗粒的大小和分布类似于正常胎儿前列腺，但不同于正常成人和增生前列腺。综合分析ＡｇＮＯＲ的数量、大小和分布有助于前列腺良、恶性病变的鉴别诊断。Automatic image- analysis technique was applied to the quantita tive studies on AgNOR in prostatictissues and carcinomas.The results s howed that AgNOR in prostatic earcinoma(PC , 27)is 4. 65土0.68,in benignprostate hyperplasia(PH , 19 ) is 2. 4l ± 0. 26 , in normal adult prostate(NP,4)is l. 37±0.13,in normal fetalprostate(FP,5)is3. 43± 0. 96;singnificant differences were found in guantity of AgNOR in the four above -listed. Sizeand distribution of A gNOR in PC were similar to those in FP,but were differe nt fr om those in NP a nd PH. Thesynthetic an alysis of quan tity and d istribution of AgNOR m ay be helpfuI to diagnoStic differntiation of malignancyan d be nign lesions in the prostatic portion.

关 键 词：前列腺肿瘤 AGNOR染色 定量分析 自动图象分析 

分 类 号：R737.250.4[医药卫生—肿瘤]