恶性肿瘤患者麻醉前和手术后的红细胞免疫粘附功能及血清溶菌酶动态观察  

^Changes of Immune Functions in Red Blood Cells and Lysozyme before and after Operation in Malignant Tumor Patients

作　　者：张汉生[1] 刘俊杰[1] 

机构地区：[1]武汉同济医科大学附属协和医院麻醉科

出　　处：《同济医科大学学报》1995年第2期138-141,共4页Acta Universitatis Medicinae Tongji

摘　　要：对４２例肿瘤患者麻醉前和麻醉手术后的红细胞免疫粘附功能及血清溶菌酶进行了动态观察。结果：麻醉手术后１ｈ红细胞Ｃ_３ｂ受体花环、红细胞免疫复合物花环及血清溶菌酶明显减少（Ｐ＜０．０５或＜０．０１），持续２４ｈ或４８ｈ后才逐渐恢复至术前值。这种减少可能与麻醉、手术后病人应激状态下，激素水平增高抑制了红细胞Ｃ_３ｂ受体的功能有关，但也很难排除异氟醚、局麻药等麻醉药对免疫细胞的直接作用。Immune functions of red blood cells and serum dyxozym were studied in 42 tumor patients during operations.The values were rapidly decreased(P<0.05 or P<0.01)one hour after anesthesia and recovered to normal levels 24 hours or 48 hours after anesthesia.These changes may related to the high level of hormones produced by stress reactions,which inhibit the functions of C3b receptors in red blood cells.

关 键 词：恶性肿瘤 麻醉 外科手术 红细胞免疫 溶菌酶 

分 类 号：R730.56[医药卫生—肿瘤]