杀虫双中毒死者血液、胃及肝中原型物及其代谢物分析  

Analysis of blood,stomach and liver samples from Shachongshuang intoxicated persons

作　　者：王绪卿[1] 赵云峰[1] 冯燕[1] 陈惠京[1] 林媛真[1] 韩清岭 

机构地区：[1]中国预防医学科学院营养与食品卫生研究所,湖北省公安厅刑科所

出　　处：《卫生研究》1995年第6期346-349,共4页Journal of Hygiene Research

基　　金：1992~1994年国家自然科学基金

摘　　要：采用高效薄层色谱法（ＨＰＴＬＣ）、ＯＶ－１７填充柱和ＯＶ－１０１毛细管柱火焰光度检测器－气相色谱法（ＦＰＤ－ＧＣ）以及气相色谱－质谱法（ＧＣ－ＭＳ）对３例杀虫双中毒死者的血、胃及肝样品进行分析。在血、胃及肝样品中未检出杀虫双，均检出沙蚕毒素。在血样品中还检出了比沙蚕毒素更大的色谱峰，在胃样品中也检出了此色谱峰，但峰面积较小，肝样品未见此相应的色谱峰。经实验推断此化合物为杀虫双的另一代谢产物二甲基沙蚕毒素。The blood,stomach and liver samples from 3 persons who died of intoxication of Shachongshuang were analyzed by HPTLC, OV-17 packed column, OV-101 Capillary column GC-FPD and GC-MS. In all these samples no Shachongshuang was found, but Nereistoxin was detected.In the blood sample,a peak that was bigger than that of Nereistoxin was detected.The same peak was also detected in the stomach samples,but it was smaller than in blood samples. This peak was not detected in the liver samples. The peak was determined as dimethylnereistoxin.

关 键 词：农药中毒 杀虫双 代谢物 血 胃 肝 

分 类 号：R595.404[医药卫生—内科学]