图形视诱发电位在弱视诊断及治疗中的应用  

The Application of the Pattern Visual-evoked Potential in the Diagnosis and Treatment of Amblyopia

作　　者：邵慈慧[1] 孙云翔[1] 韩玮[1] 甫拉提[1] 张莹[1] 高力[1] 杨鸿斌 

机构地区：[1]新疆医学院生理教研室,新疆830054 [2]空军乌鲁木齐医院眼科,新疆830000

出　　处：《眼科学报》1995年第2期108-110,共3页Eye Science

摘　　要：目的:研究图形视诱发电位(Pattern Visual-Evoked Potential,PVEP)在弱视诊断和治疗中的应用价值,探讨弱视发病的机制。方法:检测对象分为弱视组(108只眼)、正常对照组(180只眼)和美多巴治疗组(26只眼)。以日本光电公司产MEB—5100型诱发反应记录仪进行检测,视觉刺激采用黑白翻转方格,视角为30’、60’和 90’。叠加128次。结果:弱视组P_1波潜伏时延长,振幅降低. 30'视角P_1波潜伏时延长检出率最高,为68.5％。美多巴治疗后P_1波潜伏时缩短、振幅增高(P<0.05)。结论:选用30’视角的刺激,以P_1波潜伏时监测弱视患者的视功能较为理想,其阳性率高。PVEP是弱视诊断和疗效评价的重要客观指标。眼科学报 1995;11:108—110。Purpose: To research into the value of the application in the diagnosis and treatment of amblyopia, and to discuss the mechanism of amblyopia. Methods: The subjects were divided into three groups; 108 amblyopia eyes; 180 normal eyes and 26 amblyopia eyes during the treatment with Madopar. PVEP was observed with black-white checks pattern-reversal stimulation at several spatial frequencies (30', 60', 90').Results: P1 latency of the amblyopia eyes prolongs at the high frequency (30' angle of view) , in which the occurrence rate of abnormal PVEP is 68- 5%. Through detecting PVEP during the treatment of amblyopia with Madopar, we found P1 latency shortened and amplitude increased (P<0. 05).Conclusion : It is better to use P1 latency to observe the visual function of patients with amslyopia with stimulation at 30' angle of view. PVEP is an important objective index in diagnosis and evaluating the curative effect of amblyopia. Eye Science 1995; 11-.108-110.

关 键 词：视诱发电位 弱视 PVEP 诊断 治疗 

分 类 号：R777.44[医药卫生—眼科]