药源性谵妄58例  

Drug-Induced Delirium-A 58 Cases Report

作　　者：曾昭祥[1] 刘琳[1] 卢士臣 张永东[1] 

机构地区：[1]山东省济宁市精神病防治院,272151

出　　处：《药物流行病学杂志》1995年第4期214-216,共3页Chinese Journal of Pharmacoepidemiology

摘　　要：对58例药源性谵妄进行了分析,发现药源性谵妄根据其临床症状的不同可分为三种类型,即急性兴奋性谵妄、运动过少性谵妄及混合性谵妄.引起谵妄的精神药物以氯氮平居多,其次是氯丙嗪及阿米替林;用药至发生谵妄时间及谵妄消失时间长短不一,可能与个体差异有关.本文还对药源性谵妄的发生机制进行了简要讨论.58 patients with drug-induced delirium were analyzed and it was found that drug-induced delirium falls into three categories: acute agitative delirium, hypoactivity delirium and mixed-type delirium according to the clinic symptoms. The main delirium-inducing antipsy-chotic drug was clozapine and next come chlorpromazine and amitryptiline. The intervals between the start of medication and onset or disappearance varied, which might be related with individual heterogeneity. The mechanism of drug-induced delirium was also discussed.

关 键 词：药源性精神障碍 谵安 病例报告 

分 类 号：R749.61[医药卫生—神经病学与精神病学] R971.4[医药卫生—临床医学]