oxLDL、Lp(a)与脑血管疾病的关系  

Oxidized LDL and Lipoprotein(a) in patients with cerebrovascular disorders

作　　者：徐桂芝[1] 张万忠[1] 金宇宣[1] 

机构地区：[1]上海医科大学华山医院神经病学研究所,200040

出　　处：《中风与神经疾病杂志》1995年第2期87-88,共2页Journal of Apoplexy and Nervous Diseases

摘　　要：测定51例脑血管病和20例对照组的血浆oxLDL和血清Lp(a)。结果脑血管病组明显高于对照组,脑血管病各分组(脑出血、脑栓塞、蛛网膜下腔出血)的oxLDL亦高于对照组,脑出血、脑梗塞分组的Lp(a)高于对照组。oxLDL及Lp(a)异常与患者的性别、年龄、病程及常规血脂检查异常率无相关。结论:oxLPL、Lp(a)升高与脑血管病发病密切相关,是估价中风危险因素重要的、独立的脂蛋白参数之一。We measured the oxidized LDL(oxLDL) of plasma and lipoprotein (a) [Lp(a)] levels of serum on 51 patients with cerebrovascular dissorders and 20 cases of control group. A-mong 51 patients with cerebrovascular disorders,three groups of patients were included: patients with cerebral hemorrhage (CH), cerebral infarction (CD,and subarachnoid hemorrhage (SAH). The results revealed a significant difference on oxLDL levels in plasma between all patients groups and control group,either way on Lp(a). Morever.it showed the elevation of oxLDL and Lp(a) had no correlation with sex ,age,period of disease and the abnormal rate of routine blood lipid test. It was concluded that the elevation of oxLDL and Lp (a) is involved in the pathogenesis of cerebrovascular disorders. Lp(a) and oxLDL are important and independent lipoprotein parameters in evaluating the risk factors of cerebrovascular disorders.

关 键 词：脑血管疾病 中风 病因 低密度脂蛋白 脂蛋白 

分 类 号：R743.02[医药卫生—神经病学与精神病学] R743.3[医药卫生—临床医学]