小剂量阿斯匹林对男性中老年脑卒中发病的一级预防作用  

PRIMARY PREVENTION EFFECT OF LOWDOSE ASPIRIN ON STROKE IN MIDDLE-AGEDAND SENILE MALES

作　　者：马亚东[1] 邱小莹[1] 王丽[1] 

机构地区：[1]内蒙古自治区医院

出　　处：《中国慢性病预防与控制》1995年第2期73-74,共2页Chinese Journal of Prevention and Control of Chronic Diseases

摘　　要：３９４８名中老年人基线调查，缺血性脑卒中（ＡＩＣＨ）年发病率为６．５９‰，出血性脑卒中（ＡＨＣＨ）年发病率为１．７７‰。每日服用单剂阿斯匹林（ＡＳＡ）４Ｏｍｇ～８０ｍｇ，连续观察４年。ＡＩＣＨ年均发病率下降至５．４９‰（ｔ＝９．９４６，Ｐ＜０．００１），而ＡＨＣＨ年均发病率无明显变化（１．７４‰，ｔ＝０．３４９，Ｐ＞０．０５）。提示小剂量ＡＳＡ对男性中老年人ＡＩＣＨ发病有显著预防作用，且不增加ＡＨＣＨ危险性。In the baseline survey of 3948 middleaged and senilemales,the annual morbidity of ischemic stroke(IS ) andhemorrhagic stroke(HS)was 6.59‰ and 1.77‰respec-tively. Single dose(40mg)of aspitin(ASA)ws given dailyand followed-up for 4 years.The mean annual morbidityof IS reduced to 5.49‰(r=9.946,P<.001),but there was no significant change in the mean annual morbidity of HS1.74‰,t=0.349,P>0.05).The results suggested that low dose aspirin evidently effected the prevention of IS in middle-aged and senile males,but did not increase the risk of HS.

关 键 词：阿斯匹林 中风 一级预防 预防 

分 类 号：R743.301[医药卫生—神经病学与精神病学]