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作 者:余毅 徐智民[1] 智发朝[1] 李俊达[1] 周殿元[1]
机构地区:[1]广东省顺德市大良仁爱医院消化科,广州市南方医院消化科
出 处:《中国微生态学杂志》1995年第2期15-18,共4页Chinese Journal of Microecology
摘 要:本研究通过对2306例次胃镜检查、尿素酶试验及胃粘膜活检涂片革兰氏染色检测Hp及GH,以了解这二种病原菌在各种上消化道疾病,尤其是慢性胃炎和消化性溃疡中的作用。结果:本组病例Hp的检出率明显较低,并与病情不成比例;从1655例中筛检出37例GH病例,检出率为2.24%,主要表现为轻度慢性浅表性胃炎32例(86.5%),GH混合Hp感染7例(18.9%)。本研究结果表明:目前在一些较发达地区,Hp的感染率有降低趋势,目前清除Hp的治疗尚存在很多困难,GH相关性胃炎主要表现慢性胃炎,Hp与GH混合感染并非少见;胃镜下活检涂片革兰氏染色镜检和尿素酶试验是二种简便有效的诊断Hp和GH感染的方法,应该在胃镜检查作出病理形态学诊断的同时,作出病因学的诊断,以完善诊断和指导治疗。Helicobacter pylori(H. pylori)and Gastrospirillum hominis(G.hominis)were detected in 2306 patients by gastroendoscopy,ureasetest(UAT)and Gram′s tain of specimens smeared with gastric mucosa,for the study of gastric microecology in upper digestive tube diseases.Results:The detecting rate of H. pylori was lower than before,and was out of proportion to the patient′s condition, 37 cases of G.hominis infection were detected from 1655 subjects(rate2.24%),Mostof these patients(86.5%)suffered from mild chronic superficial gastr-itis, and 7 cases mixed infection with H. pylori(18.9%),Conclusi-ons:H. pylori infective rate was potential lower in some more develo-ped areas, but it is still hard to eradicated H. pylori infection. G.hominis-associated gastritis most shows chronic gastrtis.G. hominismixed infection with H. pylori is not few. Microscopy of mucosa smearby endo. copic biopsy and UAT are two simple and effective methodsto detecting the infection of H. pylori or G. hominis, which should beperformed to get etiologic diagnosis while pathological diagnosis isgotten.
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