爱肌松与潘侃朗宁肌松作用的临床研究  

Clinical Research of Muscular Relaxation Induced by Alcuronium and Pancuronium

作　　者：龚志毅[1] 叶铁虎[1] 裴立惠 罗霞[1] 罗爱伦[1] 刘良玉[1] 王景辉 

机构地区：[1]中国医学科学院中国协和医科大学协和医院

出　　处：《中国医学科学院学报》1995年第4期301-304,共4页Acta Academiae Medicinae Sinicae

摘　　要：４０例全麻患者随机分为４组，以观察囊肌松和潘侃朗宁肌松效应。神经肌肉接头功能监测结果表明，０．３ｍｇ／ｋｇ囊肌松的起效时间和维持时间分别为２．４ｍｉｎ和６３ｍｉｎ，０．１ｍｇ／ｋｇ潘侃朗宁的起效时间和维持时间分别为２．７ｍｉｎ和７０ｍｉｎ。上述剂量可满足气管插管和外科对肌松的需要。肌松剂注入前后未见血压、心率及血钾、血钠明显变化。The clinical experiment was designed for observing effect of muscular relaxation induced by alcuronium and pancuronium.40 patients were randomtly divided into alcuronium group(A)and Pancuronium group(P).A group and P group were redivided into A1,A2 groups and P1,P2 groups according to differences of the initial doses of muscle relaxants.The results of neuromuscular monitoring indicate that onset time and main-tenance time of 0.3mg/kg alcuronium were respectively 2.4 min and 63 min;0.1mg/kg pancuronium were 2.7 min and 70 min, The initial doses mentioned above are suitable to intubation of anesthesia and meet surgical need for muscular relaxation.The changes of MAP,HR,blood kalium and natrium were not evident in statistical significance before and after administration of relaxants.

关 键 词：爱肌松 潘侃朗宁 肌松效应 药理 

分 类 号：R971.8[医药卫生—药品]