零交导数与多波长系数分光光度法测定复方阿司匹林中3组分的含量  

Determination of three components in compound aspirin tablets by zero-crossing derivative spectrophotometry and multiwave-length coefficientspectrophotometry

作　　者：李晓妮[1] 白小红[1] 彭小丽[1] 牛建民 赵大成[1] 

机构地区：[1]山西医学院药学系,山西省传染病医院药房,山西省职业病防治所

出　　处：《中国药学杂志》1995年第12期743-745,共3页Chinese Pharmaceutical Journal

摘　　要：用零交导数及多波长系数分光光度法测定了复方阿司匹林片中阿司匹林、扑热息痛、咖啡因的含量。２种方法简单、快速且均不需分离样品。多波长系数法３组分回收率分别为９９．８１％，１００．３８％，９９．８７％。ＲＳＤ分别为１．０％，０．３％，０．９％。零交导数法３组分回收率分别为９９．１８％，１００．８１％，９８．８７％，ＲＳＤ分别为１．１％，０．８％，１．４％。Aspirin,paracetamol and caffeie in compound aspirin tablets were determined byusing zero-crossing derivative spectrophoton1etry( CDS)and multiwave-length coefficient spec-trophotometry(MCS)without being separated.The recovery for these components was 99.18%,100. 81%,98. 87%to ZDS and 99.81%. 100.38%, 99. 87%to MCS respectively. The RSD forthem was 1.1%,0.8%,1.4%to ZDS and 1,0%,0.3%,0.9%to MCS respectively.

关 键 词：分光光度法 扑热息痛 咖啡因 乙酰水杨酸 片剂 

分 类 号：R927.2[医药卫生—药学]