高分辨率CT扫描对抗肿瘤药物性肺损害的临床应用价值  

Clinical application value of high-resolution CT to anticancer drug-induced pulmonary lesions

作　　者：鲍伟宇 张森 尤云峰 

机构地区：[1]河南科技大学第三附属医院洛阳东方医院特检科,洛阳471003

出　　处：《中国实用医刊》2010年第10期16-17,共3页Chinese Journal of Practical Medicine

摘　　要：目的 探讨抗肿瘤药物性肺损害的高分辨率CT(HRCT) 表现及其临床应用价值.方法 回顾性分析诊断明确的12例抗肿瘤药物性肺损害的患者胸部HRCT表现.结果 本组抗肿瘤药物性肺损害HRCT 表现为间质性肺炎和肺纤维化7例,闭塞性细支气管炎伴机化性肺炎2例,嗜酸细胞性肺炎1例,过敏性肺炎2例.结论 抗肿瘤药物性肺损害的影像学表现是非特异性的,HRCT可以清楚的显示肺损害的病理改变,及早发现肺损害并对一些疾病的鉴别诊断有所帮助,对临床制定或修改治疗方案有重要的提示或指导意义.Objective To investigate HRCT findings of anticancer drug-induced pulmonary lesions and its clinical application value. Methods HRCT findings in 12 patients with diagnosis explicit anticancer drug-induced pulmonary lesions were retrospectively analyzed. Results The group of anticancer drug-induced pulmonary lesions HRCT findings of seven cases of interstitial pneumonia and interstitial fibrosis, bronchiolitis obliterans organizing pneumonia two cases, one case of acidophilia granular cell pneumonia, one case of allergic pneumonia. Conclusions HRCT findings of anticancer drug-induced pulmonary lesions are non-specific, and HRCT can clearly show that the pulmonary lesion to the pathological changes, and to detect the pulmonary lesion as soon as possible, develop or modify the clinical treatment has important suggestion or guidance significance.

关 键 词：抗肿瘤药物 药物性肺损害 高分辨率体层摄影 

分 类 号：R737.31[医药卫生—肿瘤]