丙烯酸胶原微球与聚乙烯醇颗粒治疗子宫肌瘤的术后反应对比  

Comparison of using tris-acryl gelatin microspheres and polyvinyl alcohol particles for uterine artery embolization in the treatment of leiomyoma of uterus

作　　者：林振文[1] 初虹[2] 窦永充[1] 张彦舫[1] 

机构地区：[1]深圳市人民医院介入科,广东518020 [2]深圳市第二人民医院妇产科,广东518035

出　　处：《放射学实践》2011年第1期79-81,共3页Radiologic Practice

基　　金：深圳市重点学科项目资助(2001B07)

摘　　要：目的:对比丙烯酸胶原微球(TAGM)与聚乙烯醇颗粒(PVA)两种不同栓塞剂治疗子宫肌瘤的术后反应及安全性。方法:26例症状性子宫肌瘤患者在知情同意下被随机分成两组行子宫动脉栓塞(UAE)术,A组(12例)栓塞剂采用丙烯酸胶原微球(Embosphere,500～700μm),B组(14例)采用PVA颗粒(500～700μm)。观察患者栓塞后综合征的严重程度和持续时间、治疗前后症状改善情况,以及栓塞剂用量。结果:两组在栓塞后综合征、治疗前后症状改善方面差异无统计学意义(P>0.05),均无严重并发症发生,在栓塞剂用量上两组差异存在统计学意义(P<0.05),A组>B组。结论:丙烯酸胶原微球作为一种新型的栓塞剂,与PVA相比,不会加重术后反应,具有较好安全性,但栓塞剂用量较大。Objective:To compare the post-treatment reaction and safety of tris-acryl gelatin microspheres(TAGM) and polyvinyl alcohol particles(PVA) in uterine arteries embolization(UAE) for the treatment of leiomyoma of uterus.Methods:26 patients with symptomatic uterine leiomyoma determined on a voluntary basis to be a candidate and scheduled for UAE were randomly divided into two groups.TAGM(Embosphere,500~700μm) was used as the embolic agent in group A(12 cases),and PVA(500~700μm) in group B(14 cases).The degree o...

关 键 词：子宫肿瘤 子宫动脉栓塞术 介入治疗 血管造影术 数字减影 

分 类 号：R737.33[医药卫生—肿瘤]