肝切除术前PEIT治疗小肝癌28例  

THE EFFICACY OF PRE-OPERATIVE PERCUTANEOUS ETHANOL INJECTION THERAPY FOR SMALL HEPATOCELLULAR CARCINOMA,28 CASES REPORT

作　　者：晏建军[1] 沈军[1] 黄亮[1] 周飞国[1] 张向化[1] 严以群[1] 

机构地区：[1]东方肝胆外科医院肝外一科,上海200438

出　　处：《肝胆外科杂志》2011年第1期17-20,共4页Journal of Hepatobiliary Surgery

摘　　要：目的探讨可切除的小肝癌术前PEIT的临床价值。方法 2000年1月~2002年11月收治的67例可切除小肝癌患者随机分成术前PEIT组(n=28)与I期手术组(n=39)所有患者术后病理均证实为肝细胞癌。对比两组标本间肿瘤坏死、纤维包膜、子灶、门静脉血栓、肝硬化等病理情况。结果术前PEIT组较I期手术组肿瘤坏死广泛、包膜形成率更高,且术前PEIT组中有28.6%的患者有门静脉血栓形成。术前PEIT组术后1、3、5年复发率分别为10.7%、14.3%和25%,Ⅰ期手术组术后1、3、5年复发率分别为11.3%、24.5%和36.7%;术前PEIT组术后1、3、5、10年生存率分别为83.9%、78.6%、71.4%和53.6%,Ⅰ期手术组术后1、3、5、10年生存率分别为89.7%、69.2%、61.5%和41%。结论术前PEIT安全可行,并能显著降低小肝癌患者肝切除术后的复发率,提高长期生存率。Objective This study was designed to investigate the efficacy of pre-operative percutaneous ethanol injection therapy(PEIT) for small hepatocellular carcinoma(small HCC). Methods From January 2000 to November 2002,67 patients with resectable samll HCC were prospectively randomized into two groups:preoperative PEIT group(n=28) and one-stage operation group(n=39). All patients were proven HCC histologically after hepatectomy. The pathological changes of resected specimens were compared between two groups incl...

关 键 词：肝细胞癌 无水酒精瘤内注射 肝切除 

分 类 号：R735.7[医药卫生—肿瘤]