对甲酚与2,4-二叔丁基酚对斑马鱼的联合毒性研究  

Joint Toxicity of P-Cresol and 2,4-Di-Tert-Butylphenol on Zebrafish(Brachydanio rerio)

作　　者：房妮[1] 张松林[2] 俱国鹏[1] 白芳铭 

机构地区：[1]陕西省灾害监测与机理模拟重点实验室宝鸡文理学院,陕西宝鸡721007 [2]西北师范大学地理与环境科学学院,甘肃兰州730070 [3]河北旭阳焦化有限公司,河北定州073000

出　　处：《江西农业学报》2010年第11期122-124,共3页Acta Agriculturae Jiangxi

基　　金：甘肃省教育厅基金项目(0801-08);甘肃省自然科学基金项目(2007GS03614);甘肃省重点学科生态经济学;陕西省重点学科自然地理学资助项目;宝鸡文理学院重点科研项目(ZK08122)

摘　　要：以静水法测试了对甲酚与2,4-二叔丁基酚对斑马鱼的单一和联合急性毒性,并以毒性单位分析法和Marking相加指数法对其联合毒性效应类型进行了判定。结果表明:对甲酚的单一毒性为中毒,2,4-二叔丁基酚的单一毒性为高毒。Marking相加指数法和毒性单位分析法对两者的联合毒性作用的评价结论一致:在等毒性配比下,对甲酚与2,4-二叔丁基酚的24、48、72和96 h时联合毒性均为拮抗作用。The single and joint acute toxicities of P-cresol and 2,4-di-tert-butylphenol on zebrafish(Brachydanio rerio) were examined by the static test method,and the type of joint toxicity effect was determined by the Marking's additive index(AI) and the toxicity unit analysis(TU).The results showed that the single acute toxicity of P-cresol was moderate,and that of 2,4-di-tert-butylphenol was high.The toxicity assessment conclusions had no difference between these two methods.The joint toxicity of P-cresol and 2,4-di-tert-butylphenol(toxicity 1∶1) was all antagonistic at 24 h,48 h,72 h and 96 h.

关 键 词：对甲酚 二叔丁基酚 斑马鱼 联合毒性作用 相加指数法 毒性单位 单一毒性 联合毒性效应 分析法 静水法测试 拮抗作用 急性毒性 中毒 判定 结果 

分 类 号：S[农业科学]